One of the top Week 1 NFL predictions from the model: The Los Angeles Chargers (-3.5) open up their season with a six-point win at home against the Las Vegas Raiders. Now, the model has simulated the entire Week 1 NFL schedule 10,000 times and generated its optimal NFL pick'em plays. More importantly for NFL confidence pool players, the model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94 percent of CBS Sports office pool players four times during that span. The model enters the 2022 NFL season on an incredible 138-97 run on top-rated NFL picks that dates back to the 2017 season. The model, which simulates every NFL game 10,000 times, is up over $7,500 for $100 players on top-rated NFL picks since its inception. This week features several season-opening storylines, but which are the ones to pay attention to as you review the Week 1 NFL spreads and make your NFL football pool picks? Before you make your NFL predictions, you need to see the Week 1 NFL football pool picks from SportsLine's proven model. That's 15 games left to choose in your first set of matchups for NFL confidence pool picks and NFL office pool picks. After 14 games on the Sunday NFL slate, the first week of the new season culminates with the Russell Wilson Bowl on Monday Night Football between his former team, the Seattle Seahawks and his new team, the Denver Broncos.
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